Work in the Lab

See the work being done in the Applied Science 480 Capstone Lab!

 

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Here, the students are using a technique known as extrusion to create bacterial cell mimics and isolate large unicellular vesicles (LUVs). These cell mimics can be used in conjunction with a technique called circular dichroism to obtain structural information about membrane-interacting peptides. These data can be used to establish structure-function relationships in antimicrobial peptides that act at lipid membranes.

 

 

Circular Dichroism:

Watch our students explain this peptide analysis method:

 

Preparing Lipid Films:

Lipid films are used for NMR oriented sample preparation and CD experiments to model membranes.

 

Explanation of the NMR magnet:

How does William and Mary generate a 17 tesla magnetic field? Find out!